Adjust dose according to blood glucose levels during the first few months.
Use in pregnancy & lactation: Use during pregnancy is contraindicated (see Contraindications).
Studies have not been conducted in nursing mothers but caution should be exercised in such patients and a decision should be made to discontinue nursing or to discontinue Panfor SR, taking into account the importance of metformin HCl to the mother.
Use in children: Safety and effectiveness in children has not been established.
Use in the elderly: As aging is associated with reduced renal function, care should be taken in dose selection and should be based on careful and regular monitoring of renal functions.